Last update Dec. 2, 2022
Low Risk
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Trospium Chloride in other languages or writings:
Trospium Chloride belongs to this group or family:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 9.6 (4.0 - 16.1) | % |
Molecular weight | 428 | daltons |
Protein Binding | 50 - 85 | % |
VD | 5.6 ± 2.0 | l/Kg |
pKa | 11.05 | - |
Tmax | 5.3 ± 1.2 | hours |
T½ | 18.3 ± 3.2 | hours |
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Antimuscarinic with atropine-like effects. Indicated in the treatment of overactive bladder. Oral administration once or twice a day.
At the date of the last update, we did not find any published data on its excretion in breast milk.
Its large volume of distribution makes its passage to breast milk in a clinically significant amount unlikely.
Its low oral bioavailability (even lower if taken with food) hinders the transition to plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
Milk production should be monitored, as there are reports (albeit few and old) that anticholinergics can reduce prolactin levels. (Masala 1982).