Last update May 21, 2021

Tolnaftate

Low Risk

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Topical antifungal effective in the treatment of superficial dermatophytosis (ringworm) and pityriasis versicolor.
Pediatric use authorized from 2 years.
1% topical application twice a day for 2 to 6 weeks.

At the date of the last update, the authors did not find any published data on its excretion in breast milk.

The small dose and poor plasma absorption of most topical dermatological preparations make it unlikely that a significant amount will pass into breast milk.
The absorption of tolfnaphtate in the dermis is less than 1 microgram/cm2 (Kezutyte 2010).

Do not apply on the breasts to prevent the infant from ingesting it; if necessary, apply after one feeding and clean well with water before the next.

Alternatives

We do not have alternatives for Tolnaftate.

Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Tolnaftate in other languages or writings:

Group

Tolnaftate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Tolnaftate in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 307 daltons

References

  1. AEMPS-Galenicum Derma. Cuatrocrem. Ficha técnica. 2017 Full text (in our servers)
  2. Kezutyte T, Kornysova O, Maruska A, Briedis V. Assay of tolnaftate in human skin samples after in vitro penetration studies using high performance liquid chromatography. Acta Pol Pharm. 2010 Jul-Aug;67(4):327-34. Abstract

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