Last update Oct. 14, 2022
Compatible
We do not have alternatives for Ticarcillin Sodium; Ticarcillin Disodium since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Ticarcillin Sodium; Ticarcillin Disodium in other languages or writings:
Ticarcillin Sodium; Ticarcillin Disodium belongs to this group or family:
Main tradenames from several countries containing Ticarcillin Sodium; Ticarcillin Disodium in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 0 | % |
Molecular weight | 428 | daltons |
Protein Binding | 54 | % |
pKa | 3.09 | - |
Tmax | 0.5 - 1 | hours |
T½ | 1.1 | hours |
Theoretical Dose | 0.3 - 0.38 | mg/Kg/d |
Relative Dose | 0.36 - 0.46 | % |
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e-lactancia is a resource recommended by IHAN of Spain
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It is a carboxypenicillin used in the treatment of serious gram-negative infections, especially those due to Pseudomonas aeruginosa. Intravenous administration.
It is excreted into breastmilk in a clinically insignificant amount. (Matsuda 1984, von Kobyletzki 1983)
Its null oral bioavailability minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal flora in infants whose mothers take antibiotics should be taken into account. (Ito 1993).
Expert authors consider the use of this medication to be safe during breastfeeding. (LacMed, Briggs 2015)