Last update Aug. 20, 2022

Sugammadex Sodium


Safe substance and/or breastfeeding is the best option.

It is a modified gamma-cyclodextrin that binds to rocuronium or vecuronium, reversing its neuromuscular blocking action. Used intravenously.

Since the last update we have not found published data on its excretion in breast milk.

Its high molecular weight makes it unlikely that it will pass into milk in significant amounts.

Its low oral bioavailability would make it difficult its passage to the infant’s plasma through breast milk. (EMA 2017)

Side effects are rare and mild. It is administered in single or isolated doses.

Sugammadex can be used during breastfeeding. (LactMed, EMA 2017)


Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Sugammadex Sodium in other languages or writings:


Main tradenames from several countries containing Sugammadex Sodium in its composition:


Variable Value Unit
Oral Bioavail. ≈ 0 %
Molecular weight 2.178 daltons
Protein Binding 0 %
VD 0.2 l/Kg
pKa 2.82 -
2 hours


  1. EMA. Sugammadex. Ficha técnica. 2017 Full text (in our servers)
  2. EMA. Sugammadex. Drug Summary. 2017 Full text (in our servers)
  3. Reece-Stremtan Sarah, Campos Matilde, Kokajko Lauren, and The Academy of Breastfeeding Medicine. Breastfeeding Medicine. ABM Clinical Protocol #15: Analgesia and Anesthesia for the Breastfeeding Mother, Revised 2017. Breastfeed Med. 2017 Nov;12(9):500-506. Full text (link to original source) Full text (in our servers)

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