Last update Dec. 13, 2019

Sodium bicarbonate


Safe substance and/or breastfeeding is the best option.

It is contained in preparations used for treatment of excessive gastric acidity, oral rehydration solutions and fluids for intravenous use that aim the correction of acute metabolic acidosis. Also used for long-standing treatment of chronic metabolic acidosis due to kidney malfunction.

Oral bicarbonate solutions neutralize gastric acidity with production of Carbon Dioxide. The rest is absorbed by the gut. In the plasma, bicarbonate is kept at normal physiological range, with the excess eliminated by the kidney.

Epithelial cells of the mammary gland regulate the entrance of sodium and bicarbonate into the mother's milk, with little effect on milk composition due to diet (Ereman 1987).

Bicarbonate and other antacids do not concentrate in breast milk and are considered safe during breastfeeding (Mahadevan 2006).

Bicarbonate decreases secretion of Prolactin in cases of secondary Hyperprolactinemia due to metabolic acidosisinduced by exercise, but does not affect production of the milk (Rojas 2006).

WHO Model List of Essential Medicines 2002: compatible with breastfeeding (WHO 2002).

Sodium and potassium acetates, sodium and potassium citrates and sodium lactate, after absorption are metabolized to bicarbonate.

See below the information of these related products:


We do not have alternatives for Sodium bicarbonate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Sodium bicarbonate is also known as

Sodium bicarbonate in other languages or writings:


Sodium bicarbonate belongs to these groups or families:


Main tradenames from several countries containing Sodium bicarbonate in its composition:

  • Alka-Seltzer
  • Antiacid™. Contains other elements than Sodium bicarbonate in its composition
  • Arcid™. Contains other elements than Sodium bicarbonate in its composition
  • Betsol Z
  • Bicarnat
  • Darmen™. Contains other elements than Sodium bicarbonate in its composition
  • Elgydium Blancheur™. Contains other elements than Sodium bicarbonate in its composition
  • Hospasol


Variable Value Unit
Molecular weight 84 daltons


  1. Rojas Vega S, Strüder HK, Wahrmann BV, Bloch W, Hollmann W. Bicarbonate reduces serum prolactin increase induced by exercise to exhaustion. Med Sci Sports Exerc. 2006 Abstract
  2. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  3. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  4. Ereman RR, Lönnerdal B, Dewey KG. Maternal sodium intake does not affect postprandial sodium concentrations in human milk. J Nutr. 1987 Abstract
  5. Hanssen KF, Torjesen PA. Increased serum prolactin in diabetic ketoacidosis; correlation between serum sodium and serum prolacting concentration. Acta Endocrinol (Copenh). 1977 Abstract

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