Last update Jan. 23, 2023

シメチコン

Compatible

Safe substance and/or breastfeeding is the best option.

Simethicone is an activated form of dimethicone used to treat flatulence orally. Dimethicone is a fluid type of silicone with a methyl as organic group radical. Silicones are polymers of silicon tied to oxygen atoms with high molecular weight.

At latest update, relevant published data on excretion into breast milk were not found.

Because it is not absorbed through the skin or orally (Briggs 2015, Mahadevan 2006) along with a very high molecular weight, excretion into breast milk in significant amount or absorption by the infant gut is highly unlikely.

It is also a drug approved for use in young infants, under 3 months. (Gordon 2018, Lucassen 2010)

Expert authors consider the use of simethicone to be probably safe during breastfeeding. (Hale, LactMed, Briggs 2015, Mahadevan 2006, Nice 2000, Hagemann 1998)

Alternatives

We do not have alternatives for シメチコン since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

シメチコン is Simeticone, Simethicone in Japanese.

Is written in other languages:

シメチコン is also known as

Group

シメチコン belongs to this group or family:

Tradenames

Main tradenames from several countries containing シメチコン in its composition:

List of 127 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 238.461 daltons

References

  1. LactMed. Drugs and Lactation Database (LactMed). Internet. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/ 2006 - Consulted on April 16, 2024 Full text (link to original source)
  2. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on April 10, 2024 Full text (link to original source)
  3. Gordon M, Biagioli E, Sorrenti M, Lingua C, Moja L, Banks SS, Ceratto S, Savino F. Dietary modifications for infantile colic. Cochrane Database Syst Rev. 2018 Oct 10;10:CD011029. Abstract
  4. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  5. Lucassen P. Colic in infants. Clin Evid (Online). 2010 Abstract Full text (link to original source) Full text (in our servers)
  6. Simeticona Ficha técnica 2009 Full text (in our servers)
  7. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  8. Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000 Nov;16(4):319-31. Review. Erratum in: J Hum Lact 2001 Feb;17(1):90. Abstract
  9. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract

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