Last update March 11, 2015

センノシド

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Indian Senna, Senna or Tinnevelly Senna. Shrub. Leaves, fruits, and flowers are used.

It contains anthraquinones, naphtoquinones, flavonoids, mineral salts, polysaccharides (mucilage).

Unproved effect: Irritant of intestine. Not absorbed by GI tract, laxative.

American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Alternatives

We do not have alternatives for センノシド since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

センノシド is also known as Senna. Here it is a list of alternative known names::


Groups

センノシド belongs to these groups or families:

Tradenames

Main tradenames from several countries containing センノシド in its composition:

List of 55 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 863 daltons
Theoretical Dose 0.0041 mg/Kg/d
Relative Dose 0.24 %

References

  1. Bunchorntavakul C, Reddy KR. Review article: herbal and dietary supplement hepatotoxicity. Aliment Pharmacol Ther. 2013 Abstract Full text (link to original source) Full text (in our servers)
  2. Budzynska K, Gardner ZE, Dugoua JJ, Low Dog T, Gardiner P. Systematic review of breastfeeding and herbs. Breastfeed Med. 2012 Abstract Full text (link to original source) Full text (in our servers)
  3. WHO. World Health Organization. WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS). WHO monographs. 2010 Full text (in our servers)
  4. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  5. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  6. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  7. Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000 Nov;16(4):319-31. Review. Erratum in: J Hum Lact 2001 Feb;17(1):90. Abstract
  8. WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume I. WHO monographs 1999 Full text (link to original source) Full text (in our servers)
  9. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  10. Gattuso JM, Kamm MA. Adverse effects of drugs used in the management of constipation and diarrhoea. Drug Saf. 1994 Abstract
  11. Grospietsch G. [Is Agiolax safe in pregnancy and lactation?]. Med Monatsschr Pharm. 1991 Abstract
  12. Faber P, Strenge-Hesse A. Sennahaltiges Laxans: Übertritt in Muttermilch? \ [Senna-containing laxatives: excretion in the breast milk?]. Geburtshilfe Frauenheilkd. 1989 Abstract
  13. Faber P, Strenge-Hesse A. [Senna-containing laxatives: excretion in the breast milk?]. Geburtshilfe Frauenheilkd. 1989 Abstract
  14. Faber P, Strenge-Hesse A. Relevance of rhein excretion into breast milk. Pharmacology. 1988 Abstract
  15. Shelton MG. Standardized senna in the management of constipation in the puerperium: A clinical trial. S Afr Med J. 1980 Abstract
  16. Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973 Abstract
  17. Werthmann MW Jr, Krees SV. Quantitative excretion of Senokot in human breast milk. Med Ann Dist Columbia. 1973 Abstract
  18. BALDWIN WF. Clinical Study of Senna Administration to Nursing Mothers: Assessment of Effects on Infant Bowel Habits. Can Med Assoc J. 1963 Abstract Full text (link to original source) Full text (in our servers)
  19. DUNCAN AS. Standardized senna as a laxative in the puerperium; a clinical assessment. Br Med J. 1957 Abstract Full text (link to original source) Full text (in our servers)

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