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Secnidazole is a derivative of 5-nitroimidazole with properties similar to those of metronidazole. It is used in the treatment of amebiasis, giardiasis and trichomoniasis. Oral administration, one or two doses in a single day (5 days if hepatic amebiasis).
At the date of the last update we found no published data on its excretion in breast milk.
Its pharmacokinetic data (low molecular weight and low protein binding) make it likely to pass into breast milk in quantities that could be significant.
There is no evidence in the scientific literature that it is carcinogenic or mutagenic and it is very unlikely that there is any risk from taking a single dose (FDA 2017). Used in children from 5 kg of weight (Novag 2011), in children under 6 months (Rodriguez 2011, Goto 2009, Toppare 199) or one year of age. (Aventis 2011)
Until more published data on this drug in relation to breastfeeding are known, safer and shorter half-life alternatives may be preferable, especially during the neonatal period and in case of prematurity.