Last update June 10, 2018

Ruscogenin

Compatible

Safe substance and/or breastfeeding is the best option.

A sapogenin obtained from the roots of the ruscus aculeatus shrub. Used topically to treat hemorrhoids and varicose veins.

Since the last update we have not found published data on its excretion in breast milk.

The small dose and low plasma absorption of most topical dermatological preparations make it unlikely that a significant amount will transfer into breastmilk.

Some cases of contact dermatitis have been detected after the topical use of antihemorrhoidal ointments that included ruscogenin in their composition (Gonzalo-Garijo MA et al 2009, Cordoba et al 2009, Ramírez-Hernández M. et al 2006).
For the sake of prudence and to avoid contact with the baby’s skin, it is recommended that you wash your hands well after applying the cream.


See below the information of this related product:

Alternatives

We do not have alternatives for Ruscogenin since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Ruscogenin is also known as


Ruscogenin in other languages or writings:

Group

Ruscogenin belongs to this group or family:

Tradenames

Main tradenames from several countries containing Ruscogenin in its composition:

List of 11 tradenames
  • Abrasone Rectal™. Contains other elements than Ruscogenin in its composition
  • Flebodolor™
  • Ibuproct™. Contains other elements than Ruscogenin in its composition
  • Miopropan Proctologico™. Contains other elements than Ruscogenin in its composition
  • Perfluxi Cremagel™. Contains other elements than Ruscogenin in its composition
  • Procto Venart™. Contains other elements than Ruscogenin in its composition
  • Proctolog™. Contains other elements than Ruscogenin in its composition
  • Recbutin™. Contains other elements than Ruscogenin in its composition
  • Ruscoroid™. Contains other elements than Ruscogenin in its composition
  • Ruscus™. Contains other elements than Ruscogenin in its composition
  • Ruskorex™. Contains other elements than Ruscogenin in its composition

Pharmacokinetics

Variable Value Unit
Molecular weight 431 daltons

References

  1. Córdoba S, Martínez-Morán C, Hernández-Nuñez A, Borbujo J. Contact dermatitis from an anti-haemorroidal cream containing ruscogenin. Eur J Dermatol. 2009 Abstract
  2. Gonzalo-Garijo MA, Pérez-Calderón R, Chaves-Alvarez A, Pérez-Rangel I, Rodríguez-Nevado I. Compound allergy to an antihemorrhoidal ointment demonstrated by the repeated open application test. J Investig Allergol Clin Immunol. 2009 Abstract
  3. Ramírez-Hernández M, García-Sellés J, Mérida-Fernández C, Martínez-Escribano JA. Allergic contact dermatitis to ruscogenins. Contact Dermatitis. 2006 Abstract
  4. [No authors listed] Ruscus aculeatus (butcher's broom). Monograph. Altern Med Rev. 2001 Abstract Full text (link to original source) Full text (in our servers)

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