Last update May 1, 2022
Compatible
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(RS)-5-Methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulphinyl)benzimidazole is Omeprazole in Chemical name.
Is written in other languages:(RS)-5-Methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulphinyl)benzimidazole is also known as
(RS)-5-Methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulphinyl)benzimidazole belongs to this group or family:
Main tradenames from several countries containing (RS)-5-Methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulphinyl)benzimidazole in its composition:
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Proton pump inhibitor (PPI), reducing gastric acid secretion. Oral administration once or twice a day.
Its pharmacokinetic data (very high percentage of plasma protein binding and short half-life) explain the negligible passage to milk observed. (Marshall 1998)
No problems have been observed in infants of mothers who took omeprazole (Marshall 1998). Possible adverse reactions are rare and not serious. (Dexcel 2021, AEMPS 2017)
Shown to be labile in acid-pH environment must be administered in the form of micro-granules within an enteric-coated capsule (AEMPS 2017): any small quantity reaching the infant's stomach would be readily inactivated.
Authorized use in children from one year of age. It has been used in newborns
A similar product, pantoprazole, also has negligible excretion in breast milk and did not cause problems in the infant.(Plante 2004)
Manufacturers (Dexcel 2021, AEMPS 2017) and expert authors (Rowe 2013, Nava 2006) consider that the risk of affecting the infant is very unlikely.
Omeprazole and other PPIs can cause hyperprolactinemia, galactorrhea, and gynecomastia. (Prikis 2020, He 2019, Jabbar 2010)
See below the information of this related product: