Last update June 17, 2017

Rimantadine Hydrochloride

Low Risk

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

An antiviral used in the prophylaxis of influenza A.

Since the last update we have not found published data on its excretion in breast milk.

Its use is authorized for children from one year of age.
Its large volume of distribution makes it unlikely that milk will pass through in significant amounts.
Possible side effects are rare and mild.

Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.

Alternatives

  • Amantadine Hydrochloride (Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)
  • Oseltamivir Phosphate ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Zanamivir ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Rimantadine Hydrochloride in other languages or writings:

Group

Rimantadine Hydrochloride belongs to this group or family:

Tradenames

Main tradenames from several countries containing Rimantadine Hydrochloride in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 92 %
Molecular weight 216 daltons
Protein Binding 40 %
Tmax 6 hours
T1/2 25 (13 - 65) hours

References

  1. FDA. Rimantadine. Drug Summary. 2010 Full text (in our servers)
  2. Anderson EL, Van Voris LP, Bartram J, Hoffman HE, Belshe RB. Pharmacokinetics of a single dose of rimantadine in young adults and children. Antimicrob Agents Chemother. 1987 Abstract

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