Last update Dec. 21, 2022
Compatible
We do not have alternatives for Rilpivirine (RPV) since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
Rilpivirine (RPV) in other languages or writings:
Main tradenames from several countries containing Rilpivirine (RPV) in its composition:
Variable | Value | Unit |
---|---|---|
Molecular weight | 366 | daltons |
Protein Binding | > 99 | % |
VD | 2.2 - 2.5 | l/Kg |
pKa | 11.43 | - |
Tmax | 3 - 4 | hours |
T½ | 34 - 55 | hours |
M/P ratio | 1.1 | - |
Theoretical Dose | 0.02 | mg/Kg/d |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Antiretroviral. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against HIV-1. It is used alone or in combination with other antiretrovirals in the treatment of HIV infection and AIDS. Oral administration once daily.
It is excreted in breast milk in clinically insignificant amounts. (Aebi 2022)
Plasma levels of infants whose mothers were taking it were very low, less than 4% of maternal plasma levels. (Aebi 2022)