Last update Jan. 15, 2022

Quercetin

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Bioflavonoid compounds are widely distributed in nature. Onion has a rich content of Quercetin. Flavonoids are phenolic compounds naturally occurring that are abundantly present in all plants and in some seaweed.

They are ingested when drinking fruits, vegetables, tea and red wine, for example. (Serafini 1996)

Most important types are: anthocyanins, chalcons, flavonols, flavones, flavonoids and tannins. 

Attributed anti-oxidant activity and other properties that have not been fully shown yet (Martinez 2016, Morling 2015, Cohen 2012, AESAN 2012), as amelioration of capillary vessel function which is a reason to be used for treatment of venous insufficiency (varicose veins) and prevention of arteriosclerosis. 

They appear naturally in the breast milk in amounts related to mother's diet. (Romaszko 2014, Song 2013)

No risk for toxic nor side-effects in humans have been found (AESAN 2012). No problems have been observed in infants whose mothers were treated with troxerutin. (Krajnovic 1977)

The maximum acceptable daily intake amount for quercetin is 75 mg. (AESAN 2012)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Quercetin is also known as


Quercetin in other languages or writings:

  • Кверцетин (Cyrillic)
  • 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one (Chemical name)
  • C15H10O7 (Molecular formula)

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 52 %
Molecular weight 302 daltons
pKa 6.44 -
Tmax 0.6 - 2 hours
11 - 18 hours

References

  1. Martinez-Zapata MJ, Vernooij RW, Uriona Tuma SM, Stein AT, Moreno RM, Vargas E, Capellà D, Bonfill Cosp X. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2016 Abstract
  2. Morling JR, Yeoh SE, Kolbach DN. Rutosides for treatment of post-thrombotic syndrome. Cochrane Database Syst Rev. 2015 Abstract
  3. Romaszko E, Wiczkowski W, Romaszko J, Honke J, Piskula MK. Exposure of breastfed infants to quercetin after consumption of a single meal rich in quercetin by their mothers. Mol Nutr Food Res. 2014 Abstract
  4. AESAN. Informe del Comité Científico de la Agencia Española de Seguridad Alimentaria y Nutrición (AESAN) sobre condiciones de uso de determinadas sustancias distintas de vitaminas, minerales y plantas para ser empleadas en complementos alimenticios - 1. Revista del comité científico nº 17. 2012 Full text (in our servers)
  5. Cohen JM, Akl EA, Kahn SR. Pharmacologic and compression therapies for postthrombotic syndrome: a systematic review of randomized controlled trials. Chest. 2012 Abstract
  6. Kienzler JL, Sallin D, Schifflers MH, Ghika A. Pharmacokinetics of mono-3'- and mono-4'-0-(beta-hydroxyethyl)-rutoside derivatives, after single doses of Venoruton powder in healthy volunteers. Eur J Clin Pharmacol. 2002 Abstract
  7. Graefe EU, Wittig J, Mueller S, Riethling AK, Uehleke B, Drewelow B, Pforte H, Jacobasch G, Derendorf H, Veit M. Pharmacokinetics and bioavailability of quercetin glycosides in humans. J Clin Pharmacol. 2001 Abstract
  8. Olthof MR, Hollman PC, Vree TB, Katan MB. Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans. J Nutr. 2000 Abstract Full text (link to original source) Full text (in our servers)
  9. McAnlis GT, McEneny J, Pearce J, Young IS. Absorption and antioxidant effects of quercetin from onions, in man. Eur J Clin Nutr. 1999 Abstract
  10. Serafini M, Ghiselli A, Ferro-Luzzi A. In vivo antioxidant effect of green and black tea in man. Eur J Clin Nutr. 1996 Abstract
  11. Krajnovic P. [The influence of the combination of coumarin and troxerutin on infantile blood parameter in lactation period. Short communication (author's transl)]. Arzneimittelforschung. 1977 Abstract

Total visits

18,650

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by IHAN of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM