Last update June 10, 2018
Very High Risk
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Propyphenazone is also known as
Propyphenazone in other languages or writings:
Propyphenazone belongs to this group or family:
Main tradenames from several countries containing Propyphenazone in its composition:
|Protein Binding||10 - 20||%|
|Tmax||1 - 3||hours|
|T½||1 - 1.5||hours|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
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An analgesic derived from pyrazolone, inhibitor of prostaglandin synthesis by inhibiting cyclooxygenase.
Administered orally and rectally.
Since the last update date we have not found published data on its excretion in breastmilk.
Severe hemolytic anemia has been reported in a newborn whose mother was taking it (Frei 1985).
Since 1989, it has been withdrawn from sale in many countries for having caused medullary aplasia, Lyell's syndrome and other serious side effects (Onakpoya 2018).
It is marketed in multiple preparations that combine caffeine, codeine, atropine and anti-inflammatory drugs. In general, drug combinations are not recommended and even less so during breastfeeding.
Known alternatives which are safer during breastfeeding are preferred, especially during the neonatal period and in the case of prematurity.