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Prilocaine is an amide-type local anesthetic with actions and uses similar to lidocaine. It is used for infiltration anesthesia and nerve blocks, for analgesia and epidural anesthesia, and for dental procedures. It is also used for superficial skin anesthesia in a eutectic mixture with lidocaine in cream form under occlusive dressing.
As at the time of the last update, we found no published data on its excretion in breast milk.
Topical anesthetics (well applied dermatological and stomatological preparations) have virtually no systemic absorption, as is the case with prilocaine. (Essink 1999, Vickers 1997)
Do not apply on the chest or, if necessary, apply after a feeding and clean well with water before the next feeding. Application of prilocaine/lidocaine mixture over large areas or orally may cause methemoglobinemia. (Touma 2001)
It is advisable to avoid applying creams, gels and other products containing kerosene (mineral oil) on the nipple so that the infant does not absorb it. (Concin 2008, Noti 2003)