Last update Nov. 14, 2023

Pneumococcal Vaccines

Compatible

Safe product and/or breastfeeding is the best option.

Pneumococcal vaccines are used for active immunization against Streptococcus pneumoniae infection. The vaccine consists of the capsular polysaccharide antigens of the serotypes that most frequently cause the disease. Intramuscular administration.

After vaccination during pregnancy or immediate postpartum, IgA and IgG antigens against S. pneumoniae were detected in breast milk, with good levels for about 6 months after birth (Martinovich 2022, Obaro 2004, Lehmann 2003, Finn 2002, Shahid 1995), as well as significantly higher concentrations of pneumococcal antibodies in infants at birth and months later. (Munoz 2001, Shahid 1995)

Colostrum from vaccinated mothers causes strong inhibition of pneumococcal adherence to pharyngeal epithelial cells. (Deubzer 2004)

Exclusive breastfeeding for at least 3 months results in better serologic protection against Hib and pneumococcal serotypes 6B and 14 after vaccination compared to less breastfed children. (Silfverdal 2007)

Several medical societies and expert authors consider safe to use this vaccine during lactation. (CDC 2023 and 2011, Red Book 2021-2024 p108-9, CAV-AEP 2019, Lawrence 2016 p402, Taylor 2003, Briggs 2015, Sachs 2013, Raney 2012, Chen 2010, WHO 2002).

VACCINES AND BREASTFEEDING:

(RedBook 2021-2024, CDC 2023, 2011 y 2000, Taylor 2019, Lawrence 2016 p402, Sachs 2013, Munoz 2013, Raney 2012, Perin 2012, Gall 2012, Chen 2010, Pisacane 2010, Schmidt 2004, López 2002, Pickering 1998, Pabst 1997, Hahn 1990)

Vaccines are compatible with lactation, both live attenuated microorganisms and killed, inactivated or formed by parts or toxoids of the same or generated by recombinant technology.

They do not pass into milk, except for rubella, which does not usually infect the infant or only mildly, and do not cause problems in infants, except for yellow fever in infants under 6 months of age. 

Breastfeeding may improve the antibody response of vaccines and cause fewer side effects such as fever or anorexia. 

Immediate postpartum is the best time to vaccinate measles-rubella-mumps and varicella in women who were not immunized.

Breastfeeding women can and should be protected with the recommended vaccines as other adults.

Breastfed infants should be immunized according to the appropriate immunization schedule.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

Pneumococcal Vaccines in other languages or writings:

Group

Pneumococcal Vaccines belongs to this group or family:

References

  1. Martinovich KM, Seppanen EJ, Bleakley AS, Clark SL, Andrews RM, Richmond PC, Binks MJ, Thornton RB, Kirkham LS. Evidence of maternal transfer of antigen-specific antibodies in serum and breast milk to infants at high-risk of S. pneumoniae and H. influenzae disease. Front Immunol. 2022 Sep 21;13:1005344. Consulted on Nov. 13, 2023 Abstract
  2. Deubzer HE, Obaro SK, Newman VO, Adegbola RA, Greenwood BM, Henderson DC. Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae. J Infect Dis. 2004 Nov 15;190(10):1758-61. Epub 2004 Oct 7. Consulted on Nov. 13, 2023 Abstract
  3. Obaro SK, Deubzer HE, Newman VO, Adegbola RA, Greenwood BM, Henderson DC. Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy. Pediatr Infect Dis J. 2004 Nov;23(11):1023-9. Consulted on Nov. 13, 2023 Abstract
  4. Lehmann D, Pomat WS, Riley ID, Alpers MP. Studies of maternal immunisation with pneumococcal polysaccharide vaccine in Papua New Guinea. Vaccine. 2003 Jul 28;21(24):3446-50. Review. Consulted on Nov. 13, 2023 Abstract
  5. Finn A, Zhang Q, Seymour L, Fasching C, Pettitt E, Janoff EN. Induction of functional secretory IgA responses in breast milk, by pneumococcal capsular polysaccharides. J Infect Dis. 2002 Nov 15;186(10):1422-9. Epub 2002 Oct 23. Consulted on Nov. 13, 2023 Abstract
  6. Munoz FM, Englund JA, Cheesman CC, Maccato ML, Pinell PM, Nahm MH, Mason EO, Kozinetz CA, Thompson RA, Glezen WP. Maternal immunization with pneumococcal polysaccharide vaccine in the third trimester of gestation. Vaccine. 2001 Dec 12;20(5-6):826-37. Consulted on Nov. 13, 2023 Abstract
  7. Shahid NS, Steinhoff MC, Hoque SS, Begum T, Thompson C, Siber GR. Serum, breast milk, and infant antibody after maternal immunisation with pneumococcal vaccine. Lancet. 1995 Nov 11;346(8985):1252-7. Consulted on Nov. 13, 2023 Abstract
  8. CDC- ACIP. Vaccine Recommendations and Guidelines of the ACIP. Special Situations. Breastfeeding and Vaccination. - 2023 Consulted on Oct. 25, 2023 Full text (link to original source)
  9. CDC - Centers for Disease Control and Prevention. Vaccination Safety for Breastfeeding Mothers. Breastfeeding and Special Circumstances. 2023 Full text (link to original source) Full text (in our servers)
  10. (Red Book). AAP. Kimberlin DW, Barnett ED, , Lynfield R, Sawyer MH eds. Red Book: 2021-2024. Report of the Committee on Infectious Diseases. 32th ed. Elk Grove Village, - 2021
  11. Taylor CM, Shelton CM. Vaccine recommendations in pregnancy and lactation. J Am Pharm Assoc (2003). 2019 Jan - Feb;59(1):137-140. Abstract
  12. CAV-AEP. Comité asesor de vacunas de la Asociación Española de Pediatría. Lactancia materna y vacunas. None 2019 Full text (link to original source) Full text (in our servers)
  13. Lawrence RA, Lawrence RM. Breastfeeding. A guide for the medical profession. Eighth Edition. Philadelphia: Elsevier; 2016
  14. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  15. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  16. Raney EC, El-Ibiary SY. Immunizations and pregnancy: an update for pharmacists. J Am Pharm Assoc (2003). 2012 Abstract
  17. CDC. National Center for Immunization and Respiratory Diseases. General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011 Abstract Full text (in our servers)
  18. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (in our servers)
  19. Pisacane A, Continisio P, Palma O, Cataldo S, De Michele F, Vairo U. Breastfeeding and risk for fever after immunization. Pediatrics. 2010 Abstract Full text (in our servers)
  20. Silfverdal SA, Ekholm L, Bodin L. Breastfeeding enhances the antibody response to Hib and Pneumococcal serotype 6B and 14 after vaccination with conjugate vaccines. Vaccine. 2007 Feb 9;25(8):1497-502. Epub 2006 Oct 30. Abstract
  21. Schmidt JV, Kroger AT, Roy SL. Report from the CDC. Vaccines in women. J Womens Health (Larchmt). 2004 Abstract
  22. López-Alarcón M, Garza C, Habicht JP, Martínez L, Pegueros V, Villalpando S. Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization: possible roles of interleukin-1beta, tumor necrosis factor-alpha and leptin. J Nutr. 2002 Abstract Full text (in our servers)
  23. Pickering LK, Granoff DM, Erickson JR, Masor ML, Cordle CT, Schaller JP, Winship TR, Paule CL, Hilty MD. Modulation of the immune system by human milk and infant formula containing nucleotides. Pediatrics. 1998 Feb;101(2):242-9. Abstract
  24. Pabst HF, Spady DW, Pilarski LM, Carson MM, Beeler JA, Krezolek MP. Differential modulation of the immune response by breast- or formula-feeding of infants. Acta Paediatr. 1997 Abstract
  25. Hahn-Zoric M, Fulconis F, Minoli I, Moro G, Carlsson B, Böttiger M, Räihä N, Hanson LA. Antibody responses to parenteral and oral vaccines are impaired by conventional and low protein formulas as compared to breast-feeding. Acta Paediatr Scand. 1990 Abstract

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