Last update April 17, 2016

Phentermine

Very High Risk

Very unsafe. Contraindicated. Use of an alternative or cessation of breastfeeding. Read the Comment.

Psychostimulant drug that is used as an anorectic in the treatment of obesity.

With similar action than Dexamphetamine. It can cause insomnia, anorexia and nervousness.

At latest update no published data were found on excretion into breast milk.
Pharmacokinetic data make it likely the passage into milk in an amount that may be significant.

Breastfeeding women usually regain their body weight, previous to pregnancy, sooner than those who do not breastfeed.

Given the increased risk for cardiac valvular disorders and psychotic reactions, the European Medicines Agency (EMA) ordered the withdrawal from marketing in the European Union on 2000.

Alternatives

  • Hypocaloric Diet ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Phentermine in other languages or writings:

Group

Phentermine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Phentermine in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 149 daltons
Protein Binding 18 %
VD 4.8 l/Kg
Tmax 4 - 6 hours
7 - 20 hours

References

  1. AEMPS Retirada del mercado de los medicamentos anorexígenos de acción central. 2000 Full text (in our servers)
  2. Beckett AH, Bélanger PM. The metabolism, distribution and elimination of chlorphentermine in man. Br J Clin Pharmacol. 1977 Abstract

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