Last update Oct. 17, 2022

Passion Flower

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Aerial summits of this climbing plant are used. Constituents are: flavonoids, pyranics, heterosides, alkaloids. Attributed effects with only weak scientific evidence on effectiveness are: sedative, hypnotic, anti-spasmodic. (, EMA 2008, WHO 2007)

At latest update, relevant information on excretion into breast milk was not found.

Because of paucity of data on toxicity, recommendations done are to use it at low doses for short term periods. Poisonings have occurred from the consumption of preparations of this plant. (Fisher 2000, Solbakken 1997)

The European Medicines Agency does not authorize its use for children younger than 12 years old, pregnancy and breastfeeding. (EMA 2008)

When used while breastfeeding, it is recommended to use it at low dose for a short-term period. Following-up the infant for sedation is recommended.

Precautions when taking plant preparations (Anderson 2017, Powers 2015, Posadzki 2013, Efferth 2011, Kopec 1999, Hsu 1995):

  • Make sure they are from a reliable source: poisonings have occurred due to confusion of one plant with another with toxic properties (Hsu 1995), poisonings due to containing heavy metals extracted from the soil, and food poisoning due to contamination with bacteria or fungi. (Anderson 2017)
  • Do not take in excess; follow the recommendations of expert phytotherapy professionals. “Natural” products are not good in any quantity: plants contain active substances from which much of our traditional pharmacopoeia has been obtained and can cause poisoning or act as endocrine disruptors if consumed in quantity or for an exaggerated time because they contain phytoestrogens. (Powers 2015, Zava 1998)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Passion Flower belongs to this group or family:


Main tradenames from several countries containing Passion Flower in its composition:


  1. Vanaclocha B, Cañigueral S. 1992 - - Disponible en: Consulted on June 9, 2022 Abstract
  2. Anderson PO. Herbal Use During Breastfeeding. Breastfeed Med. 2017 Abstract
  3. Powers CN, Setzer WN. A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements. In Silico Pharmacol. 2015 Mar 22;3:4. Abstract Full text (link to original source) Full text (in our servers)
  4. Posadzki P, Watson L, Ernst E. Contamination and adulteration of herbal medicinal products (HMPs): an overview of systematic reviews. Eur J Clin Pharmacol. 2013 Abstract
  5. Efferth T, Kaina B. Toxicities by herbal medicines with emphasis to traditional Chinese medicine. Curr Drug Metab. 2011 Abstract
  6. EMEA. Passionflower Drug Summary. 2008 Full text (in our servers)
  7. EMEA. Pasiflora. Ficha técnica 2008 Full text (in our servers)
  8. WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume 3. WHO monographs. 2007 Full text (link to original source) Full text (in our servers)
  9. [No authors listed] Management of insomnia: a place for traditional herbal remedies. Prescrire Int. 2005 Abstract
  10. Fisher AA, Purcell P, Le Couteur DG. Toxicity of Passiflora incarnata L. J Toxicol Clin Toxicol. 2000 Abstract
  11. Kopec K. Herbal medications and breastfeeding. J Hum Lact. 1999 Jun;15(2):157-61. Review. No abstract available. Abstract
  12. Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Abstract
  13. Solbakken AM, Rørbakken G, Gundersen T. [Nature medicine as intoxicant]. Tidsskr Nor Laegeforen. 1997 Abstract
  14. Hsu CK, Leo P, Shastry D, Meggs W, Weisman R, Hoffman RS. Anticholinergic poisoning associated with herbal tea. Arch Intern Med. 1995 Abstract

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