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Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID), derived from propionic acid, used to treat osteoarthritis and rheumatoid arthritis. Oral administration once daily.
Since the last update we have not found published data on its excretion in breastmilk.
Its pharmacokinetic data (very high percentage of protein binding and wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.