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Dopamine is a sympathomimetic catecholamine used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output and hypotension arising from situations such as acute heart failure, cardiogenic shock, myocardial infarction, renal failure, cardiac surgery and septic shock. Intravenous infusion administration.
At the time of the last update, we found no published data on its excretion in breast milk.
Its very short elimination half-life (2 minutes) makes it very unlikely to pass into breast milk in significant quantities.
Its lack of oral bioavailability makes it difficult for it to pass into infant plasma from ingested breast milk, since it is degraded in the gastrointestinal tract and is not absorbed.
Dopamine inhibits prolactin release from the anterior pituitary (Fitzgerald 2008, Ben 2001), but once breastfeeding is established, milk secretion depends little on prolactin and there are no publications on dopamine and milk production.
Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs: compatible with Breastfeeding. (WHO 2002)