Last update Aug. 5, 2022
Very Low Risk
We do not have alternatives for Norepinephrine since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Norepinephrine is also known as
Norepinephrine in other languages or writings:
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
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It is a powerful adrenergic stimulant. It produces peripheral vasoconstriction and increases blood pressure. Used in hypotensive states such as shock and cardiac arrest. intravenous administration.
Since the last update we have not found published data on its excretion in breastmilk.
Its rapid metabolism (short TMax and T1/2, less than 1 and 3 minutes, respectively) make it very unlikely that significant quantities will pass into breast milk.
Furthermore, it is destroyed in the gastrointestinal tract. The low oral-bioavailability makes its levels into infant's plasma, that would be absorbed from ingested breast milk, be nil or negligible. (Kearney 2018)
Small amounts of norepinephrine are synthesized in the lactocyte and are present in breast milk. (Chiba 2021)
Expert authors consider the use of this medication compatible during breastfeeding. (Hale, LactMed Kearney 2018)