Last update Nov. 23, 2022
Very Low Risk
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Niacinamide (Vit. B3) is also known as
Niacinamide (Vit. B3) in other languages or writings:
Niacinamide (Vit. B3) belongs to these groups or families:
Main tradenames from several countries containing Niacinamide (Vit. B3) in its composition:
|Tmax||0.75 - 3||hours|
|T½||0.9 - 4.3||hours|
|Relative Dose||3 - 9||%|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Niacin, niacinamide, nicotinamide, nicotinic acid or vitamin B3 is one of the water soluble vitamins. It is naturally present in many foods and is available as a dietary supplement. Absorbed niacin is metabolized into the coenzyme nicotinamide adenine dinucleotide (NAD), essential to catalyze more than 400 metabolic reactions in the body related to cholesterol and fatty acid synthesis and cellular antioxidant function. Tryptophan is also a source of niacin. The daily requirement for niacin is 17 mg (or 1,000 mg tryptophan) for lactating women. Many foods contain niacin: meat, fish, whole grains, nuts, legumes... (NIH 2022 and 2019, Ares 2015, Hall 2010)
Breast milk contains niacin (1.2–2.8 mg/L) and its concentration is higher in mature milk than in colostrum and initial milk. (Allen 2019, Ren 2015)
Niacin content in breast milk is highly correlated with maternal intake (Allen 2019, Greer 2001). In healthy breastfed infants of well-nourished mothers, there is little risk of niacin deficiency. (Greer 2001)
Severe niacin deficiency causes pellagra
An excess of niacin (more than 30 mg daily) can cause skin, gastrointestinal and hepatic side effects.
Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs: compatible with Breastfeeding. (WHO 2002)
A moderate consumption of niacin without exceeding the daily requirements is compatible with lactation.