Last update March 30, 2014

Nabumetone

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Latest update failed to find relevant data on breastfeeding.

Both a high molecular weight and high plasma protein-binding makes excretion into breast milk unlikely.

The infant is further protected because of a low oral bioavailability.

Until more information on this drug concerning breastfeeding is available, a safer alternative should be preferred.

Alternatives

  • Diclofenac ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Ibuprofen ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Ketorolac Trometamol ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Paracetamol ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Piroxicam ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Tradenames

Main tradenames from several countries containing Nabumetone in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 35 %
Molecular weight 228 daltons
Protein Binding 99 %
Tmax 2 - 8 hours
25 hours

References

  1. PDR Nabumetone Drug Summary 2013 Full text (in our servers)
  2. Nabumetona Ficha técnica 2007 Full text (in our servers)

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