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The X-ray contrast media with components like Metrizoic acid, Meglumine and Sodium have a content between 52 and 60% of Iodine. It has been withhold from the market.
Metrizoate is excreted into breast milk in clinically non-significant amount: 0.3% of the maternal dose. (Nielsen, 1987)
The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk.
Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk. Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant. The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination.
Most experts and radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait no time to nurse.
American Academy of Pediatrics: medication usually compatible with breastfeeding.(AAP 2001)
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