Last update March 24, 2015


Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

It is a Macrolide-type antibiotic.

At latest update, relevant published data on excretion into breast milk were not found.

A high molecular weight makes excretion into breast milk be very unlikely.

Until more data on this medication is available, safer alternative drugs are preferred, especially in such critical age periods.

Be aware of false negative results of bacterial cultures from febrile infants, that may occur when breastfeeding mothers are taking antibiotics.


  • Clarithromycin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Erythromycin (Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Midecamycin belongs to this group or family:


Main tradenames from several countries containing Midecamycin in its composition:


Variable Value Unit
Molecular weight 814 daltons
Protein Binding 47 %
Tmax 0.5 - 1 hours
1 - 3 hours


  1. Midecamicina. Ficha técnica. 1999 Full text (in our servers)
  2. Periti P, Mazzei T, Mini E, Novelli A. Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part I). Clin Pharmacokinet. 1989 Abstract

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e-lactancia is a resource recommended by Confederación Nacional de Pediatría (CONAPEME) of Mexico

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