Mescaline

Mescaline is an alkaloid (phenylethylamine group) from the peyote cactus (Lophophora williamsii) and the San Pedro cactus (Echinopsis pachanol, Echinopsis peruviana), which grow in northern Mexico and the Peru-Ecuador-Bolivia area respectively. It has psychedelic ^{(NIH 2023)}, sympathomimetic, hallucinogenic, euphoriant, depersonalizing and psychotic properties similar to LSD, but about 2,000 times less powerful. It has a low liposolubility. Oral administration in infusion or chewed and also smoked and by insufflation. ^{(Vamvakopoulou 2023, Dinis-Oliveira 2019)}

As of the last update, we found no published data on its excretion in breast milk.

The paucity of published pharmacokinetic data does not allow prediction of the amount of possible excretion into breast milk.

May produce increased prolactin secretion ^{(Demisch 1979)}. There are reports of traditional use as a galactogogue. ^{(Rojas Arechiga 2008)}. Best galactagogue results are achieved through on-demand breastfeeding along with an adequate technique in a mother who is able to maintain self-confidence. ^{(ABM 2011, Mannion 2012)}

It is known from pharmacokinetics that after 5 elimination half-lives (T½) 96.9% of an ingested substance is eliminated from the body, and after 7 T½ the plasma concentrations of the substance are negligible and would constitute the safe waiting period for resuming breast-feeding after taking mescaline. 
Taking the published T½ (6 h) as a reference, this 7 T½ would correspond to two days. In the meantime, breast milk should be expressed and discarded regularly if breastfeeding is to be resumed.

Psychotropic drugs of abuse render the mother incapable of caring for her child, endangering the life and health of both.

Bed-sharing with the baby is not recommended if you are taking this drug.

There is no scientific evidence on the benefits and risks of psychedelic drug microdosing. ^{(NIH 2023, Kaypak 2022, de Wit 2022, Szigeti 2021, Lea 2020, Kuypers 2019)}