Last update Aug. 31, 2020

Magnesium Chloride

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Magnesium Chloride taken intravenously is used to treat acute or severe hypomagnesemia.
Various magnesium salts (aspartate, citrate, chloride, gluconate, lactate, levulinate, orotate, oxide, pidolate and sulphate) are used as mineral supplements (ATC A12CC) in the form of oral or intramuscular dietary intake in magnesium deficiency states.

Daily magnesium requirements for breastfeeding mothers are estimated at 310 to 360 mg (MedlinePlus 2017); some countries have established figures of up to 450 mg daily (Hall 2010).

Since the last update we have not found any published data on its excretion in breast milk.

Magnesium is a natural component of milk. The average natural concentration of magnesium in milk is 31 mg/L (15 to 64 mg/L) (Dórea 2000, Feeley 1983).

Ingested magnesium is not concentrated in breastmilk. Its concentration in milk is very stable and depends little on diet (USD 2000) and other factors, including intravenous administration of magnesium sulphate to the mother: the levels of magnesium in milk of mothers treated with intravenous magnesium sulphate were 6.4 mg/L versus 4.8 mg/L in untreated patients (Cruikshank 1982, Dorea 2000), a clinically non-significant difference for the infant, which also disappeared within a few hours.

Its low oral bioavailability hinders transfer to plasma and, therefore, to breastmilk, as well as transfer to infant plasma via breastmilk (Morris 1987).

In women treated with magnesium sulphate before or during childbirth, there has been a delay in the stimulation of milk production or lactogenesis II (Haldeman 1993) and less frequency of breastfeeding (Meier 2005) as well as hypotonia in newborns (Riaz 1998, Rasch 1982), which could interfere with adequate breast stimulation, but this can be counteracted by a firm decision by the mother and effective support for her (Cordero 2012).

Various medical associations and expert consensus consider the use of various magnesium salts to be safe during breastfeeding (Dennis 2012, Mahadevan 2006, Richter 2005, Nice 2000, Broussard 1998, Idama 1998).

If the intravenous administration of magnesium sulphate is considered compatible with breastfeeding, all the more reason that salts administered orally will also be compatible (Hagemann 1998).


We do not have alternatives for Magnesium Chloride since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Magnesium Chloride in other languages or writings:


Main tradenames from several countries containing Magnesium Chloride in its composition:

  • Acid Concentrate™. Contains other elements than Magnesium Chloride in its composition
  • Naturalyte H™. Contains other elements than Magnesium Chloride in its composition


Variable Value Unit
Molecular weight 95 - 203 daltons


  1. MedlinePlus. Magnesium in diet. Medical Encyclopedia 2017 Full text (link to original source) Full text (in our servers)
  2. MedlinePlus. Magnesio en la dieta. Enciclopedia médica. 2017 Full text (link to original source) Full text (in our servers)
  3. Dennis AT. Management of pre-eclampsia: issues for anaesthetists. Anaesthesia. 2012 Sep;67(9):1009-20. Abstract Full text (link to original source) Full text (in our servers)
  4. Hall Moran V, Lowe N, Crossland N, Berti C, Cetin I, Hermoso M, Koletzko B, Dykes F. Nutritional requirements during lactation. Towards European alignment of reference values: the EURRECA network. Matern Child Nutr. 2010 Oct;6 Suppl 2:39-54. Abstract Full text (link to original source) Full text (in our servers)
  5. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  6. Richter JE. Review article: the management of heartburn in pregnancy. Aliment Pharmacol Ther. 2005 Nov 1;22(9):749-57. Review. Abstract Full text (in our servers)
  7. Dórea JG. Magnesium in human milk. J Am Coll Nutr. 2000 Apr;19(2):210-9. Review. Abstract
  8. Nice FJ, Snyder JL, Kotansky BC. Breastfeeding and over-the-counter medications. J Hum Lact. 2000 Nov;16(4):319-31. Review. Erratum in: J Hum Lact 2001 Feb;17(1):90. Abstract
  9. Idama TO, Lindow SW. Magnesium sulphate: a review of clinical pharmacology applied to obstetrics. Br J Obstet Gynaecol. 1998 Mar;105(3):260-8. Review. No abstract available. Abstract
  10. Broussard CN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation: what are the safest therapy options? Drug Saf. 1998 Oct;19(4):325-37. Review. Abstract
  11. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  12. Morris ME, LeRoy S, Sutton SC. Absorption of magnesium from orally administered magnesium sulfate in man. J Toxicol Clin Toxicol. 1987;25(5):371-82. Abstract
  13. Feeley RM, Eitenmiller RR, Jones JB Jr, Barnhart H. Calcium, phosphorus, and magnesium contents of human milk during early lactation. J Pediatr Gastroenterol Nutr. 1983 May;2(2):262-7. Abstract
  14. Cruikshank DP, Varner MW, Pitkin RM. Breast milk magnesium and calcium concentrations following magnesium sulfate treatment. Am J Obstet Gynecol. 1982 Jul 15;143(6):685-8. No abstract available. Abstract

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