Last update Dec. 4, 2020

Lysozyme Hydrochloride

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

A mucopolysaccharidase present in various body fluids (saliva, breastmilk, tears) with antibacterial, antiviral and antifungal action (Giuffrida 2018, Lönnerdal 2003, Mata 1971).
It is a protein made up of approximately 130 amino acids.

Since the last update we have not found any published data in relation to breastfeeding.

Its high molecular weight makes its excretion in breastmilk highly unlikely.

Due to its protein nature, it is inactivated in the gastrointestinal tract, not being absorbed (practically nil oral bioavailability), which hinders or prevents the transfer to infant plasma from breastmilk, except in premature cases and the immediate neonatal period, when there may be increased intestinal permeability.


We do not have alternatives for Lysozyme Hydrochloride since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Lysozyme Hydrochloride is also known as

Lysozyme Hydrochloride in other languages or writings:


Main tradenames from several countries containing Lysozyme Hydrochloride in its composition:


Variable Value Unit
Oral Bioavail. 0,1 %
Molecular weight 14.000 - 20.000 daltons


  1. Giuffrida MC, Cigliana G, Spoto G. Ultrasensitive detection of lysozyme in droplet-based microfluidic devices. Biosens Bioelectron. 2018 May 1;104:8-14. Abstract
  2. Lönnerdal B. Nutritional and physiologic significance of human milk proteins. Am J Clin Nutr. 2003 Jun;77(6):1537S-1543S. Review. Abstract
  3. Mata LJ, Wyatt RG. The uniqueness of human milk. Host resistance to infection. Am J Clin Nutr. 1971 Aug;24(8):976-86. Review. Abstract

Total visits


Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at

e-lactancia is a resource recommended by IHAN of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM