Last update Jan. 6, 2021
Antiviral prescribed for profilaxis from cytomegalovirus (CMV) infeccion in recipients of allogeneic hematopoietic stem cell transplants.
Administered orally or intravenously once a day.
We could not find published data regarding the excretion of this substance through breast milk at the time this last update was completed.
Due to its pharmacokinetic data (large distribution volume, moderately high molecular weight and very high protein binding percentage: EMA 2018), it is very unlikely for any significant amounts to pass into human milk.
When it is not combined with ciclosporin, its low oral bioavailability (35%: EMA 2018) makes it very difficult for this substance to reach a breastfeeding infant´s plasma. There may be greater intestinal permeability in preterm infants and during the immediate neonatal period but even then the amount that could pass into breast milk would still be clinically negligible.
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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