Last update Nov. 2, 2023
Compatible
We do not have alternatives for カルボシステイン since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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カルボシステイン is Carbocisteine in Japanese.
Is written in other languages:カルボシステイン is also known as
Main tradenames from several countries containing カルボシステイン in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 10 | % |
Molecular weight | 179 | daltons |
VD | 0.9 | l/Kg |
pKa | 1.84 | - |
Tmax | 1 - 1.7 | hours |
T½ | 1.33 - 3.1 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Carbocisteine is an expectorant mucolytic used to alleviate respiratory diseases associated with increased mucus viscosity. Oral administration three times a day.
At the time of the last update, we found no published data on its excretion in breast milk.
Its high volume of distribution makes it unlikely to pass into breast milk in significant concentration.
The absorption from ingested mother's milk to the infant's plasma is hampered by a low oral bioavailability (Irish 2014, AEMPS 1998), with this being a reason for a nil or minimal plasma level in the infant, except in prematures or soon after birth when absorption would be higher.
It is a product that has only mild or few side-effects when used at normal dose. The manufacturer considers it probably compatible with lactation. (CINFA 2021)