Last update Dec. 1, 2004

Indinavir

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Anti-HIV drug. It has been used to treat children older than 3 years of age.
Mothers must be adviced that transmission of HIV infection through breastfeeding has been documented.

Alternatives

We do not have alternatives for Indinavir.

Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Indinavir belongs to this group or family:

Tradenames

Main tradenames from several countries containing Indinavir in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 65 %
Molecular weight 614 daltons
Protein Binding 61 %
Tmax 1,1 hours
T1/2 1,8 hours

References

  1. WHO - World Health Organization Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach. Guideline. 2016 Abstract Full text (link to original source) Full text (in our servers)
  2. CDC - Centers for Disease Control and Prevention, U.S. Department of Health and Human Services. Updated Guidelines for Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV— United States. nPEP Guidelines Update. 2016 Full text (link to original source) Full text (in our servers)

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