Last update Nov. 12, 2024

Idoxuridine

Compatible

Safe product and/or breastfeeding is the best option.

Idoxuridine is a pyrimidine nucleoside structurally related to thymidine with antiviral properties. It is used topically in the treatment of herpes simplex keratitis and cutaneous herpes simplex and herpes zoster infections. Topical ophthalmic or cutaneous application, 4 times a day for 4 days.

At the date of the last update, we found no published data on its excretion in breast milk.

The small dose and the almost nil plasma absorption rate of topical ophthalmic and dermatological preparations make it unlikely that any significant amount will pass into breast milk.

In addition, it is rapidly inactivated by deaminases or nucleotidases and is rapidly metabolized in the body to iodouracil, which is excreted in the urine. (Cecmed 2017)

Do not apply to the breast or clean well before breastfeeding.

WHO list of essential medicines: compatible with breastfeeding. (WHO-UNICEF 2002).

Alternatives

We do not have alternatives for Idoxuridine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Idoxuridine in other languages or writings:

Groups

Idoxuridine belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Idoxuridine in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 354 daltons
pKa 8.46 -

References

  1. CECMED. Idoxiuridina. Ficha técnica. 2017 Full text (in our servers)
  2. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)

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