Human Papillomavirus Vaccines (HPV)

Recombinant human papillomavirus (HPV) vaccines are prepared from purified particles of the major capsid L1 protein.  There is a bivalent vaccine against HPV types 16 and 18, a tetravalent vaccine against HPV types 6, 11, 16 and 18 and a nonavalent vaccine against HPV types 6, 11, 16, 18, 31, 33, 45, 52 and 58. They are used in girls and women 9 to 26 years of age (and in boys 12 years of age) for active immunization for the prevention of anogenital precancerous lesions and cancers and genital warts. Intramuscular administration.

Breastfed infants of mothers vaccinated with the tetravalent vaccine (Gardasil) had a higher, but not statistically significant, percentage of adverse reactions than with placebo; these reactions were not attributed to the vaccine. ^{(Garland 2009, Markowitz 2007)}

Several medical societies and expert authors consider safe to use this vaccine during lactation. ^{(CDC 2023 y 2011, Red Book 2021-2024 p108-9, Mother To Baby 2021, CAV-AEP 2019, Lawrence 2016 p402, Taylor 2003, Briggs 2015, Sachs 2013, Raney 2012, Chen 2010, WHO 2002)}

VACCINES AND BREASTFEEDING:

^{(RedBook 2021-2024, Zullo 2023, CDC 2023, 2011 y 2000, Taylor 2019, Lawrence 2016 p402, Sachs 2013, Munoz 2013, Raney 2012, Perin 2012, Gall 2012, Chen 2010, Pisacane 2010, Schmidt 2004, López 2002, Pickering 1998, Pabst 1997, Hahn 1990)}

Vaccines are compatible with lactation, both live attenuated microorganisms and killed, inactivated or formed by parts or toxoids of the same or generated by recombinant technology.

They do not pass into milk, except for rubella, which does not usually infect the infant or only mildly, and do not cause problems in infants, except for yellow fever in infants under 6 months of age. 

Breastfeeding may improve the antibody response of vaccines and cause fewer side effects such as fever or anorexia. 

The immediate postpartum period is the best time to vaccinate against measles-rubella-mumps, varicella, diphtheria-tetanus-pertussis and papillomavirus in women who were not immunized.

Breastfeeding women can and should be protected with the recommended vaccines as other adults.

Breastfed infants should be immunized according to the appropriate immunization schedule.

 

See below the information of this related product:

• Maternal Human Papillomavirus (HPV) infection (Safe product and/or breastfeeding is the best option.)