Last update Oct. 9, 2016

Gramicidin

Compatible

Safe substance and/or breastfeeding is the best option.

Polypeptide with antibacterial properties which is isolated along with tyrothricin through fermentation of Bacillus brevis.
Topically used on mucocutaneous and eye infections often in association with other antibacterial drugs such as Neomycin, Polymyxin B and others like Corticosteroids or Benzocaine.

It is highly toxic when systemically used. It has been withdrawn from the market in some countries due to lack of therapeutic effectiveness.

Given its negligible systemic absorption and high molecular weight, excretion into breastmilk is highly unlikely.

Do not apply on the breast to prevent ingestion by the infant.

Alternatives

We do not have alternatives for Gramicidin since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
DONATE NOW

Other names

Gramicidin in other languages or writings:

Groups

Gramicidin belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Gramicidin in its composition:

List of 6 tradenames
  • Flodermol™. Contains other elements than Gramicidin in its composition
  • Midacina™. Contains other elements than Gramicidin in its composition
  • Neosporin™. Contains other elements than Gramicidin in its composition
  • Oftalmowell™. Contains other elements than Gramicidin in its composition
  • Septilisin™. Contains other elements than Gramicidin in its composition
  • Sofradex™. Contains other elements than Gramicidin in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. baja - Poor %
Molecular weight 1.882 daltons

References

  1. AEMPS. Oftalmowell. Ficha técnica. 2013 Full text (in our servers)
  2. WHO Pharmaceuticals Newsletter. 2005 Full text (link to original source) Full text (in our servers)

Total visits

36,454

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM