Last update Sept. 17, 2022
Likely Compatibility
We do not have alternatives for Glycerol Phenylbutyrate; Sodium Phenylbutyrate.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Glycerol Phenylbutyrate; Sodium Phenylbutyrate is also known as
Glycerol Phenylbutyrate; Sodium Phenylbutyrate in other languages or writings:
Glycerol Phenylbutyrate; Sodium Phenylbutyrate belongs to this group or family:
Main tradenames from several countries containing Glycerol Phenylbutyrate; Sodium Phenylbutyrate in its composition:
Variable | Value | Unit |
---|---|---|
Molecular weight | 531 / 186 | daltons |
Protein Binding | 82 | % |
pKa | 4.81 | - |
Tmax | 1 - 3.74 | hours |
T½ | 0.76 - 1.15 | hours |
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e-lactancia is a resource recommended by El Parto Es Nuestro of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a drug that decreases elevated plasma levels of glutamine and ammonium in patients with urea cycle disorders. Oral administration before meals.
Since the last update we have not found published data on its excretion in breastmilk.
Its rapid metabolism to phenylacetate and short elimination half-life make it highly unlikely that clinically significant amounts will pass into breast milk.
It is a medication for use since the neonatal period.
With the correct dosage, side effects are not frequent or serious. The possibility of breastfeeding will depend more on the underlying disease and the clinical status of the mother.