Last update July 3, 2022
Increased level of risk
New scientific evidences have driven the Apilam staff to update the level of risk associated to this product.
Former level of risk, which was Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment., is now set to Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.
Level of risk reviewed on July 1, 2022
The leaves of the tree are used. It contains flavonoids (quercetin, kaempferol...), tannins, terpene lactones (ginkgolides), steroids… Properties attributed to it in traditional medicine without solid scientific evidence: venotonic agent, capillary protector, cerebral vasodilator (neuroprotective) and platelet antiaggregant (McKenna 2001, WHO 1999). Indications from Commission E of the German Ministry of Health: cerebral insufficiency, intermittent claudication and vertigo (Blumenthal 1998). The Committee on Herbal Medicinal Products (HMPC) of the European Medicines Agency (EMA) accepts its use in cognitive impairment associated with age and in adult patients with mild dementia and in mild peripheral circulatory problems: leg heaviness, coldness of hands or feet. (EMA 2015)
Since the last update we have not found published data on its excretion in breastmilk.
It has been classified as a possible human carcinogen (Group 2B) by the International Agency for Research on Cancer. (Sarecka 2022, IARC 2016)
Due to the lack of published data on this plant in relation to breastfeeding (Sachs 2013) and as it may cause side effects (Sarecka 2022, Mei 2017, Roland 2012, Leistner 2010, Etheridge 2009, Tesch 2003), most medical associations and experts discourage it during breastfeeding. (the Royal Women's Hospital 2013, Amir 2011, Dugoua 2006, Wong 1998)
Precautions when taking plant preparations (Anderson 2017, Powers 2015, Posadzki 2013, Efferth 2011, Kopec 1999, Hsu 1995):
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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