Last update Sept. 24, 2015

Flurbiprofen

Compatible

Safe substance and/or breastfeeding is the best option.

Non-steroidal analgesic drug with a similar chemical structure as Ibuprofen.

It is excreted into breast milk in non detectable or clinically non-significant amount.

Alternatives

We do not have alternatives for Flurbiprofen since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Flurbiprofen in other languages or writings:

Groups

Flurbiprofen belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Flurbiprofen in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 244 daltons
Protein Binding 99 %
VD 0.1 l/Kg
Tmax 1 - 2 hours
T½ 3 - 6 hours
M/P ratio 0.03 -
Theoretical Dose 0.01 mg/Kg/d
Relative Dose 0.3 %

References

  1. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  2. Davies NM. Clinical pharmacokinetics of flurbiprofen and its enantiomers. Clin Pharmacokinet. 1995 Abstract
  3. Lee JJ, Rubin AP. Breast feeding and anaesthesia. Anaesthesia. 1993 Jul;48(7):616-25. Review. Abstract Full text (link to original source) Full text (in our servers)
  4. Smith IJ, Hinson JL, Johnson VA, Brown RD, Cook SM, Whitt RT, Wilson JT. Flurbiprofen in post-partum women: plasma and breast milk disposition. J Clin Pharmacol. 1989 Abstract
  5. Goldsmith DP. Neonatal rheumatic disorders. View of the pediatrician. Rheum Dis Clin North Am. 1989 Abstract
  6. Cox SR, Forbes KK. Excretion of flurbiprofen into breast milk. Pharmacotherapy. 1987 Abstract
  7. Needs CJ, Brooks PM. Antirheumatic medication during lactation. Br J Rheumatol. 1985 Abstract

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