Last update Sept. 9, 2025

Ether

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Volatile liquid. The first product used in anesthesia (Campbell 1894, Coppinger 1879). Today it is not used in many countries due to its dangerous nature (highly flammable) and side effects: mucosal irritability, delirium, postanesthetic vomiting (Campbell 1894), etc. It may still be used in limited settings due to the unavailability of other anaesthetics (Morgans 2018). Administration by inhalation.Some of its derivatives, such as dimethyl ether, are still used as solvents and local anesthetics and in cosmetic products.

Since the last update we have not found published data on its excretion in breast milk. Its short half-life (Butler 1964) would allow breastfeeding as soon as the mother is awake and is in a suitable condition.

The popular custom in some cultures of applying creams containing ether on the abdomen for the purpose of slimming or firming during the postpartum period may be dangerous for the infant because of the anesthetic effects of the ether. Furthermore, as stated in the safety data sheets for this product: "Causes skin irritation... Repeated exposure may cause skin dryness or cracking". (Chemos 2019, NJ 2002)

Alternatives

  • Halothane (Safe product and/or breastfeeding is the best option.)
  • Sevoflurane (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Ether is also known as


Ether in other languages or writings:

Groups

Ether belongs to these groups or families:

Pharmacokinetics

Variable Value Unit
Molecular weight 74 daltons
Tmax 0.3 hours
0.1 - 0.25 hours

References

  1. Chemos. Ether. Ficha técnica. 2019 Full text (in our servers)
  2. Morgans LB, Graham N. Ether Anesthesia in the Austere Environment: An Exposure and Education. J Spec Oper Med. 2018 Summer;18(2):142-146. Abstract
  3. NJ. Ether. Fact Sheet. 2002 Full text (in our servers)
  4. BUTLER RA. PHARMACOKINETICS OF HALOTHANE AND ETHER. Br J Anaesth. 1964 Abstract Full text (link to original source) Full text (in our servers)
  5. Campbell GG. III. Ether Anaesthesia; Clinical Notes on 300 Cases. Ann Surg. 1894 Abstract Full text (link to original source)
  6. Coppinger C. Primary Ether Anaesthesia. Br Med J. 1879 Abstract Full text (link to original source)

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