Last update July 1, 2015
It is a first generation antihistamine drug which is related to ethanolamine, with sedative and anti-muscarinic effects. It has been used as hypnotic and for vomiting relief.
At latest update, relevant published data on excretion into breast milk were not found.
Pharmacokinetic characteristics would favour that it may be excreted into breast milk in significant amount. On a telephone survey, 10% of infants whose mothers were on several types of antihistamine medication have suffered of colicky pain and irritability that disappeared without treatment.
For both treatment of mothers and infants would be safer the use of tested antihistamine medication without sedative effect, especially in prematures and infants younger than 1 month of age.
Whenever used while breastfeeding, the use of the lower effective dose and for the shortest time as possible is recommended.
Follow-up for somnolence and feeding troubles should be warranted.
Bed-sharing is not recommended when the mother is on this medication.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM