Last update Nov. 5, 2014

Dirithromycin

Low Risk

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Be aware of the possibility of false negative bacterial cultures when the mother is on antibiotics.

Alternatives

  • Azithromycin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Clarithromycin ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Erythromycin (Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)

Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Dirithromycin belongs to this group or family:

Tradenames

Main tradenames from several countries containing Dirithromycin in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 14 %
Molecular weight 837 daltons
Protein Binding 15 %
Tmax 4 hours
T1/2 44 hours

References

  1. Chin KG, McPherson CE 3rd, Hoffman M, Kuchta A, Mactal-Haaf C. Use of anti-infective agents during lactation: Part 2--Aminoglycosides, macrolides, quinolones, sulfonamides, trimethoprim, tetracyclines, chloramphenicol, clindamycin, and metronidazole. J Hum Lact. 2001 Feb;17(1):54-65. Abstract

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