Last update Oct. 29, 2024
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Dimetindene Maleate (systemic use) in other languages or writings:
Dimetindene Maleate (systemic use) belongs to this group or family:
Main tradenames from several countries containing Dimetindene Maleate (systemic use) in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 70 | % |
Molecular weight | 409 | daltons |
Protein Binding | 90 | % |
Tmax | 2 | hours |
T½ | 6 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Amamanta of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
1st generation antihistamine, alkylamine derivative, with sedative and antimuscarinic effect. It is used orally for the symptomatic treatment of pruritus, urticaria, rhinitis, cough. In cream or gel form it is used topically in pruritus.
At the date of last update we did not find published data on its excretion in breast milk.
It has an antiprolactin effect that could inhibit lactation in the first weeks after delivery.
Although its occasional and moderate use during lactation is probably safe, until further published data on this drug in relation to lactation are available, safer known alternatives are preferable.
Monitor drowsiness and adequate feeding of the infant.
Due to its sedative effect, bed-sharing with the infant is not recommended if this drug is being taken. (UNICEF 2018, 2017, 2017, 2014, 2014, 2013 and 2006, Landa 2012, ABM 2008)
Topical use as a dermatological preparation is safe during lactation. The low cutaneous absorption (Radler 1995) and the high fixation to plasma proteins make unlikely the passage of a significant amount into breast milk. Do not apply on the breast.
See below the information of this related product: