Last update March 1, 2023

碘克沙醇

Compatible

Safe substance and/or breastfeeding is the best option.

X-ray contrast medium with 49% Iodine (150 - 320 mg/mL of iodine). Intravenous administration

It is excreted in breast milk in clinically insignificant amounts. (Chruscicki 2017)

The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk.

Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk. Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant. The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination.

Most experts and radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait no time to nurse.


See below the information of this related product:

Alternatives

We do not have alternatives for 碘克沙醇 since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

碘克沙醇 is Iodixanol in Chinese.

Is written in other languages:

Group

碘克沙醇 belongs to this group or family:

Tradenames

Main tradenames from several countries containing 碘克沙醇 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Baja - Poor %
Molecular weight 1.550 daltons
Protein Binding < 2 %
VD 0.26 l/Kg
2.1 hours
Theoretical Dose 4.2 - 8.25 mg/Kg/d
Relative Dose 0.8 - 1.5 %

References

  1. AEMPS. Iodixanol. Ficha técnica. 2022 Full text (in our servers)
  2. Chruscicki A, Morton AR, Akbari A, White CA. Composition of human breast milk in acute kidney injury. Obstet Med. 2017 Jun;10(2):79-82. Abstract Full text (link to original source)
  3. GE Healthcare. Iodixanol. Drug Summary. 2017 Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

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