Last update Nov. 5, 2024

(Corticosteroids. Corticoids)

Compatible

Safe product and/or breastfeeding is the best option.

The body's own corticosteroids (cortisol) are normally found in breast milk at an average concentration of 6 to 33 micrograms/liter. (Lawrence 2015l)

Most corticosteroids administered to the nursing mother, even at high doses of 1g (Schaefer 2015 p789), by any route are excreted in very low concentration in breast milk, clinically not significant (Nguyen 2016, Huang 2014). It is not necessary to wait any time to breastfeed after the administration of a corticosteroid by systemic or other route to the nursing mother.(Nguyen 2016).

No adverse effects have been reported in breast-fed infants with maternal use of any corticosteroid during lactation, even at high doses. 

Isolated cases of temporary reduction in milk production have been published with high doses of corticosteroids administered systemically or injected into joints or the breast. (Rosen 2023, Babwah 2013, McGuire 2012)

In topical use to treat eczema or nipple dermatosis it is advisable to choose the least potent corticosteroid, apply it just after the shot so that it has been reabsorbed before the next one; if necessary remove any remains with a gauze and do not use for more than one week in a row. Serious clinical involvement has been reported in an infant whose mother applied a corticosteroid to the nipple continuously. (De Stefano 1983)

Corticosteroids are commonly used in pediatrics and have no side effects when used alone or in short treatments.

If they are used during lactation, it is advisable to monitor milk production.

Several medical societies and expert authors consider corticosteroids, topical, systemic, inhaled, oral or nasal, ophthalmic, or rectal, to be safe and compatible with breastfeeding. (Hale, LactMed, Middleton 2020, Briggs 2015, Schaefer 2015, Mahadevan 2006, National Asthma 2004, Nice 2004)

WHO 2002 essential medicines list: breastfeeding compatible. (WHO 2002)

American Academy of Pediatrics: medication generally compatible with breastfeeding. (AAP 2001)


See below the information of these related groups:

Alternatives

We do not have alternatives for (Corticosteroids. Corticoids) since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

(Corticosteroids. Corticoids) in other languages or writings:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 80 - 100 %
Molecular weight 360 - 440 daltons
Protein Binding 40 - 90 %
VD 0.5 - 1.5 l/Kg
Tmax 0.2 - 2 hours
2 - 8 hours
M/P ratio 0.25 - -

References

  1. LactMed. Drugs and Lactation Database (LactMed). Internet. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/ 2006 - Consulted on April 16, 2024 Full text (link to original source)
  2. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on April 10, 2024 Full text (link to original source)
  3. Rosen-Carole C, Datta P, Palmiter K, Starks K, Hale TW. Transfer of Injected Triamcinolone into Human Milk of a Lactating Patient Suffering from Idiopathic Granulomatous Mastitis. Breastfeed Med. 2023 Jan;18(1):74-77. Abstract
  4. Middleton PG, Gade EJ, Aguilera C, MacKillop L, Button BM, Coleman C, Johnson B, Albrechtsen C, Edenborough F, Rigau D, Gibson PG, Backer V. ERS/TSANZ Task Force Statement on the management of reproduction and pregnancy in women with airways diseases. Eur Respir J. 2020 Feb 6;55(2). pii: 1901208. Abstract Full text (link to original source) Full text (in our servers)
  5. Nguyen GC, Seow CH, Maxwell C, Huang V, Leung Y, Jones J, Leontiadis GI, Tse F, Mahadevan U, van der Woude CJ; IBD in Pregnancy Consensus Group. The Toronto Consensus Statements for the Management of Inflammatory Bowel Disease in Pregnancy. Gastroenterology. 2016 Mar;150(3):734-757.e1. Abstract Full text (link to original source) Full text (in our servers)
  6. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  7. Schaefer C, Peters P, Miller RK. Drugs During Pregnancy and Lactation. Treatment options and risk assessment. Elsevier, Third Edition. 2015
  8. Huang VW, Habal FM. From conception to delivery: managing the pregnant inflammatory bowel disease patient. World J Gastroenterol. 2014 Abstract Full text (link to original source) Full text (in our servers)
  9. Babwah TJ, Nunes P, Maharaj RG. An unexpected temporary suppression of lactation after a local corticosteroid injection for tenosynovitis. Eur J Gen Pract. 2013 Dec;19(4):248-50. Abstract
  10. McGuire E. Sudden loss of milk supply following high-dose triamcinolone (Kenacort) injection. Breastfeed Rev. 2012 Mar;20(1):32-4. Review. Abstract
  11. Mahadevan U, Kane S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology. 2006 Jul;131(1):283-311. Review. Abstract Full text (link to original source) Full text (in our servers)
  12. Nice FJ, De Eugenio D, Dimino TA, Freeny IC, Rovnack MB, Gromelski JS. Medications and Breast-Feeding: A Guide for Pharmacists, Pharmacy Technicians, and Other Healthcare Professionals. Part I. J Pharm Technol 2004;20:17-27. doi: 10.1177/875512250402000106.
  13. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  14. De Stefano P, Bongo IG, Borgna-Pignatti C, Severi F. Factitious hypertension with mineralocorticoid excess in an infant. Helv Paediatr Acta. 1983 Abstract

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