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Ciprofibrate, a fibric acid derivative, is a lipid-regulating drug with actions on plasma lipids similar to those of bezafibrate. It decreases elevated triglyceride levels by increasing the activity of lipases that catabolize triglyceride-rich lipoproteins and decreasing LDL cholesterol levels. It also increases HDL cholesterol levels (Miller 1998). Oral administration.
At the time of the last update we found no published data in relation to lactation.
Its high binding to plasma proteins makes its passage into milk unlikely.
Due to serious side effects in patients treated with ciprofibrate, it is not marketed in many countries or restrictions have been imposed on its approved indications.
In case of administering a fibrate during lactation, it is advisable to choose those with a shorter half-life: Bezafibrate, Gemfibrozil.
For considerations on the appropriateness of lipid-lowering treatment during lactation see Maternal hyperlipidemia, hypercholesterolemia, hypertriglyceridemia.
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