Chondroitin Sulfate Sodium

Natural copolymer obtained from the cartilage of various land animals (cows) or marine animals (sharks) used in the treatment of osteoarthritis. It is a mucopolysaccharide formed by glycosaminoglycan polymers (GAG) devoid of toxicity. ^{(AESAN 2011)}

At the date of the last update, we found no published data on its excretion in breast milk.

Its very high molecular weight and high volume of distribution make it unlikely to pass into milk to any significant extent. In addition, its low oral bioavailability makes it difficult to pass into infant plasma from ingested breast milk.

It occurs naturally in the human body and in breast milk, with higher concentrations in the milk of mothers of premature infants. ^{(Coppa 2012 & 2011)}

Half of the GAGs in milk are in the form of chondroitin sulphate ^{(Coppa 2011)}, which ends up in the gastrointestinal tract of infants (Volpi 2014) and protects them from inflammation and infection. ^{(Maccari 2016, Coppa 2016, Newburg 2013, 1996 y 1995, Viveros 2004)}

Its concentration is not affected by Holder pasteurisation of milk. ^{(Coscia 2015)}

Alterations in the composition of chondroitin sulphate in milk have been detected in the case of breast cancer. ^{(Mannello 2011)}

A maximum daily amount of 500 mg of chondroitin sulphate is acceptable from a safety point of view for use as a food supplement. ^{(AESAN 2011)}