Last update Aug. 23, 2021

C14H18N2O3

Compatible

Safe substance and/or breastfeeding is the best option.

Methohexital is a short-acting barbiturate anesthetic with actions similar to thiopental, but 2 to 3 times more potent.
Used in the induction of anesthesia.
Intravenous administration.

It is excreted in breast milk in a clinically insignificant amount and no problems have been observed in infants whose mothers received it (Borgatta 1997).

American Academy of Pediatrics: Medication Usually Compatible with Breastfeeding (AAP 2001).

Alternatives

We do not have alternatives for C14H18N2O3 since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Groups

C14H18N2O3 belongs to these groups or families:

Tradenames

Main tradenames from several countries containing C14H18N2O3 in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 284 daltons
Tmax 0.01 hours
3.9 hours

References

  1. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  2. Borgatta L, Jenny RW, Gruss L, Ong C, Barad D. Clinical significance of methohexital, meperidine, and diazepam in breast milk. J Clin Pharmacol. 1997 Mar;37(3):186-92. Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM