Last update Oct. 20, 2016



Safe substance and/or breastfeeding is the best option.

Topical antifungal medication which is indicated for the treatment of mycosis of skin and nails.

At latest update relevant published data were not found on excretion into breast milk.

A negligible systemic absorption through the skin - less than 1% on intact skin and up to 4% on inflamed skin (Fromtling 1988) - makes very unlikely that significant amounts would be excreted into breast milk.

Do not apply on the breast to prevent ingestion by the infant; otherwise, do it just after a meal and clean the nipple thoroughly with water before the next feed.

Local application on the nipple of creams, gels and other products containing paraffin (mineral oil) should better be avoid to keep the infant off from absorption (Noti 2003, Concin 2008).


We do not have alternatives for ビホナゾール since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

ビホナゾール is Bifonazole in Japanese.

Is written in other languages:

ビホナゾール is also known as


ビホナゾール belongs to this group or family:


Main tradenames from several countries containing ビホナゾール in its composition:


Variable Value Unit
Oral Bioavail. <1 a 4 %
Molecular weight 311 daltons
19 - 32 hours


  1. AEMPS. Bifonazol. Ficha técnica. 2016 Full text (in our servers)
  2. Bayer. Bifonazole. Drug Summary. 2009 Full text (in our servers)
  3. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  4. Fromtling RA. Overview of medically important antifungal azole derivatives. Clin Microbiol Rev. 1988 Abstract Full text (link to original source) Full text (in our servers)
  5. Lücker PW, Beubler E, Kukovetz WR, Ritter W. Retention time and concentration in human skin of bifonazole and clotrimazole. Dermatologica. 1984 Abstract

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