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Second generation antihistamine with minimal sedative effect. Indicated for allergic and vasomotor rhinitis and allergic conjunctivitis. Oral, nasal and ophthalmic administration.
At the time of last update, no published data on breastfeeding were available.
Pharmacokinetic data (large volume of distribution, moderately high molecular weight and high percentage of plasma protein binding) make passage into breast milk unlikely in clinically significant quantities.
It is a very bitter product that could, if excreted into breast milk, alter its taste and cause rejection by the infant. (Hale).
The small dose and low plasma absorption of most topical nasal or ophthalmologic preparations make passage of significant amounts into breast milk unlikely, so they are considered safe during breastfeeding.
For oral administration, until further published data on this drug in relation to breastfeeding is known, safer alternatives may be preferable, especially during the neonatal period and in case of prematurity. (LactMed, So 2010).