Last update May 23, 2019

Amorolfine

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Antifungal for topical use.

At latest update no published data on excretion into breast milk were found.

Its negligible systemic absorption through skin or nails (Roncari 1992) make it unlikely that it will transfer into breastmilk in significant amounts (AEMPS 2018, MHRA 2011).

It has been described sporadic neonatal use without observing side effects (Fu 2013).

It is a safe and compatible product during lactation (AEMPS 2018, MHRA 2011).

Alternatives

We do not have alternatives for Amorolfine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Amorolfine is also known as


Amorolfine in other languages or writings:

Group

Amorolfine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Amorolfine in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. (Dermat: < 10%) %
Molecular weight 317 daltons
pKa 8.49 -

References

  1. AEMPS-Stada. Amorolfina. Ficha técnica. 2018 Full text (in our servers)
  2. Fu M, Ge Y, Chen W, Feng S, She X, Li X, Liu W. Tinea faciei in a newborn due to Trichophyton tonsurans. J Biomed Res. 2013 Abstract
  3. MHRA. Amorolfine. Drug Summary. 2011 Full text (in our servers)
  4. Roncari G, Ponelle C, Zumbrunnen R, Guenzi A, Dingemanse J, Jonkman JH. Percutaneous absorption of amorolfine following a single topical application of an amorolfine cream formulation. Clin Exp Dermatol. 1992 Abstract

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