Last update Jan. 19, 2023
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Amiloride Hydrochloride is also known as
Amiloride Hydrochloride in other languages or writings:
Main tradenames from several countries containing Amiloride Hydrochloride in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 50 | % |
Molecular weight | 302 | daltons |
Protein Binding | 40 | % |
VD | 5 | l/Kg |
pKa | 11.43 | - |
Tmax | 3 - 4 | hours |
T½ | 9.6 ± 1.8 | hours |
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e-lactancia is a resource recommended by La Liga de la Leche de México of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a weak, potassium-sparing diuretic that is used as an adjunct to thiazide diuretics such as hydrochlorothiazide and loop diuretics such as furosemide to conserve potassium.
It is used in the treatment of edema associated with liver cirrhosis and heart failure and in the treatment of hypertension. Oral administration once a day.
On latest update relevant data on breastfeeding were not found.
Long-term treatment with diuretic drugs may compromise the state of hydration of the nursing mother. Must make an adjustment (decrease) of the dose based on the estimated milk production and monitor milk production. Use a lower dose as possible, especially during the first postnatal month.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable (WHO 2002), especially during the neonatal period and in the event of prematurity.